Corynebacterium pseudotuberculosis wikivet english. Yersinia pseudotuberculosis infection in an adult boer. Pseudotuberculosis article about pseudotuberculosis by. The manual curation of the annotation was performed using artemis. Transfer of the virulence plasmid of yersinia pestis to. Porinebased enzyme immunoassay permits the detection of antibodies to all serological variants ofy. Corynebacterium pseudotuberculosis is a rod shaped, gram positive and aerobic bacteria. While yersinia enteritis is known to occur in adult sheep, most. The causative agents of pseudotuberculosis are microbes of the genera pasteurella and corynebacterium that are nonresistant to acids. Corynebacterium pseudotuberculosis is a member of the corynebacterium. Genotypic comparison between corynebacterium pseudotuberculosis. Overview of paratuberculosis generalized conditions merck.
Find specific details on this topic and related topics from the merck vet manual. Biotypes isolated from small ruminants and camelids are. The organism survives in environment for several months and causes disease in horses and cattle. Yersinia pseudotuberculosisis a rare cause of disease in humans. The possibility of diagnosing the disease in the early stages of infection is one advantage of the proposed method. Corynebacterium pseudotuberculosis is a species of the corynebacterium genus. The newick tree files from edgar was visualized in treeview. Short communication vector competence of musca domestica diptera. Yersiniosis, pseudotuberculosis yersinia characteristics. Pseudotuberculosis article about pseudotuberculosis by the. Yersinia pseudotuberculosis is a gramnegative bacterium which primarily causes tuberculosis like symptoms in animals. Epizootics of pseudotuberculosis are commonly seen in birds and rodents, often with high casefatality rates. Yersinia pseudotuberculosis, a gramnegative zoonotic bacterial pathogen, causes acute gastroenteritis and mesenteric lymphadenitis, which are often accompanied by fever and abdominal pain. Yersinia pseudotuberculosis gary darland, william h.
The primerdesign genesig kit for corynebacterium pseudotuberculosis c. Along with the more common yersinia enterocolitica, it can cause gastrointestinal infection in various wild and domestic animals. Corynebacterium pseudotuberculosis microbiology resource. Get a printable copy pdf file of the complete article 646k, or click on a page image below to browse page by page. The main cost of the disease to the sheep industry is through the loss of wool production that occurs in affected sheep and losses through condemnation. Humans acquire it by ingesting foods or water contaminated by animal feces.
Yersinia pestis, which causes bubonic plague, is a relatively recent offshoot, perhaps only 1,500 to 20,500 years old, of the less dangerous yersinia pseudotuberculosis, mark achtman of the max planck institute for molecular genetics in berlin and his colleagues report in the nov. See your doctor, or call healthline on 0800 611 116 for advice if you think you might have yersinia pseudotuberculosis. This is more common in people with weakened immune systems. Capsular thickening and edema granulomas with central necrosis and microabscesses immunoblasts and plasma cells in cortical and paracortical region, large lymphocytes within sinuses, germinal center hyperplasia. Infections with yersinia pseudotuberculosis serotype iii and y. The purpose of this study was to characterize the bacteria isolated from typical cla lesions in sheep from patagonia. Yersinia pseudotuberculosis article about yersinia. Pseudotuberculosis in an antbear orycteropus afer in. Corynebacterium pseudotuberculosis is the causative agent of pseudotuberculosis in sheep and of ulcerative lymphangitis in horses. Yersinia pseudotuberculosis causes zoonotic enteric infection in farm animals, wild animals, and birds.
In rare cases yersinia pseudotuberculosis infection can lead to sepsis infection in the blood. Cdc publication, center for disease control, atlanta, ga. Pure cultures of corynebacterium pseudotuberculosiswere obtained from 11 cases of. Pdf molecular characterization and antibiotic susceptibility of. Exposure response plan for laboratory handling of yersinia. We also discuss the zoonotic potential of the bacteria. A read is counted each time someone views a publication summary such as the title, abstract, and list of authors, clicks on a figure, or views or downloads the fulltext. Diagnostic comparison of corynebacterium pseudotuberculosis. The frequent use of fences with barbed wire additional file 1, traditional in the state for cattle, is inappropriate for sheep because they tend to force passage between the wires of the fence, thereby suffering lesions in the skin, opening passage for the entry of many bacteria, including c. Pseudotuberculosis, an infection caused by the ubiquitous enteropathogenic bacterium yersinia pseudotuberculosis, is a recurrent veterinary problem in livestock and zoo animals. Corynebacterium kutscheri causes pseudotuberculosis in mice.
Exposure response plan for laboratory handling of yersinia pseudotuberculosis. There was no observation of variability in the antibiotic patterns in the strains. First isolated in 1883, y pseudotuberculosis is a gramnegative bacterium that belongs to the genus yersinia in the enterobacteriaceae family. A disease of a wide variety of animal species caused by the bacterium yersinia pseudotuberculosis. Vickers, veterinary research laboratory, salisbury, rhodesia veterinary research laboratory salisbury rhodesia summary the clinical symptoms and haematological and pathological lesions of pseudotuberculosis in an antbear orycteropus afer and the biochemical and biological properties of the isolated pathogen. The kit is designed to have a broad detection profile. Etiology and pathogenesis of caseous lymphadenitis of sheep and goats c pseudotuberculosis is a grampositive, facultative, intracellular coccobacillus. Links to pubmed are also available for selected references. We present a case of corynebacterium pseudotuberculosis pneumonia in a veterinary student, with molecular genetic evidence of acquisition during labo. Yersinia pseudotuberculosis adhesins regulate tissuespecific colonization and immune cell localization in a mouse model of systemic infection.
Theres a laboratory test which can check for the disease. Specifically, the primers represent 100% homology with over 95% of the ncbi database. Pseudotuberculosis definition is any of several diseases that are marked by the formation of granulomas resembling tubercular nodules and are caused by a bacterium such as yersinia pseudotuberculosis other than the tubercle bacillus. It can be associated with postinfectious complications such as erythema nodosum and reactive arthritis, and strains of y pseudotuberculosis found. High seroprevalence of caseous lymphadenitis identified. Cheesy gland or caseous lymphadenitis cla in sheep is a bacterial disease of sheep causing abscesses in lymph nodes of the body and internal organs, especially the lungs. Learn about the veterinary topic of corynebacterium pseudotuberculosis infection of horses and cattle. Learn about the veterinary topic of overview of paratuberculosis. Yersinia pseudotuberculosis synonyms, yersinia pseudotuberculosis pronunciation, yersinia pseudotuberculosis translation, english dictionary definition of yersinia pseudotuberculosis. Pdf interaction of corynebacterium pseudotuberculosis. The main cost of the disease to the sheep industry is through the loss of wool production that occurs in. Full text full text is available as a scanned copy of the original print version. Two biotypes have been identified based on the ability of the bacteria to reduce nitrate. Pdf caseous lymphadenitis, caused by corynebacterium pseudotuberculosis, is one of the most important diseases of sheep and goats.
One to 3 weeks after the acute phase of the disease, postinfectious complications can occur. It causes caseous lymphadenitis and is involved in deep pyoderma. Positive cultures to corynebacterium pseudotuberculosis were only obtained from lesions in adult animals. Yersinia pseudotuberculosis how is yersinia pseudotuberculosis abbreviated. Pseudotuberculosis in tonsils of pigs at slaughter. Yersinia pseudotuberculosis definition of yersinia. Loss of cnfy toxininduced inflammation drives yersinia. Interaction of corynebacterium pseudotuberculosis with ovine cells in vitro article pdf available in veterinary pathology 502 june 2012 with 71 reads how we measure reads. Pseudotuberculosis yersinia pseudotuberculosis infection. Corynebacterium pseudotuberculosis longdom publishing sl. A retrospective cohort study conducted in a large school centre showed that the outbreak was strongly associated with the consumption of grated carrots served at a school lunch. Pseudotuberculous disorders of humans, now seldom called pseudotuberculosis, include actinomycosis, glanders, and nocardiosis q.
Pseudotuberculosis, any of various diseases not caused by the tubercle bacillus but marked by the formation of tuberclelike nodules. Enteritis caused by yersinia pseudotuberculosis has been reported in australian sheep, most commonly as a cause of diarrhoea in young sheep in winter and spring. Caseous lymphadenitis cl is a diesease of worldwide occurrence caused by corynebacterium pseudotuberculosis. Oct 11, 2017 yersinia pseudotuberculosis is the least common of the 3 main yersinia species that cause infections in humans. Caseous lymphadenitis of sheep and goats veterinary manual. Yersinia pseudotuberculosis infectious disease and. Use of porine from yersinia pseudotuberculosis outer coat for. Yersinia pseudotuberculosis is a coldtolerant bacterial species in the family enterobacteriaceae that most commonly causes foodborne illness, typically enterocolitis or mesenteric lymphadenitis pseudoappendicitis in children.
Once established, this disease is difficult to eradicate because drug therapy is not effective and because the clinical detection of infected animals is of limited efficiency. Pseudotuberculosis in an antbear orycteropus afer in rhodesiah. The biochemical characteristics of yersinia enterocolitica and yersinia pseudotuberculosis, 1973. Yersinia pseudotuberculosis is a gram negative, facultatively anaerobic, non sporeforming, coccoid bacillus of the genus yersinia, of the family enterobacteriaceae footnote. Pigeon fever corynebacterium pseudotuberculosis infection. The epizootiology, epidemiology, and pathogenesis of pseudotuberculosis have not been adequately studied. Pseudotuberculosis definition of pseudotuberculosis by. Withinbatch prevalence and quantification of human pathogenic yersinia enterocolitica and y. Corynebacterium pseudotuberculosis is the etiological agent of caseous lymphadenitis cla, a common disease in small ruminant populations throughout the world. Corynebacterium pseudotuberculosis infection of horses and. Yersinia pseudotuberculosis is a gramnegative bacterium that causes far east scarletlike fever in humans, who occasionally get infected zoonotically, most often through the foodborne route. Withinbatch prevalence and quantification of human. Pdf caseous lymphadenitis is a highly prevalent worldwide disease of sheep and.
Yersinia pseudotuberculosis is a rare cause of acute enteric disease with symptoms such as acute mesenteric lymphadenitis and gastroenteritis associated with abdominal pain and fever diarrhea is unusual. Corynebacterium pseudotuberculosis accedacris ulpgc. Watson department of entomology, north carolina state university, raleigh, nc 27695. Y pseudotuberculosis primarily causes zoonotic infection in various hosts, including domestic and sylvatic animals and birds, but has been associated with foodborne infection in humans. Yersinia enterocolitica, yersinia pseudotuberculosis. It causes usually mild, selflimited illnesses of mesenteric adenitis, ileitis, and diarrhea but can produce serious sepsis and abscesses in immunocompromised hosts. Yersinia pseudotuberculosis causing a large outbreak. Lyophilised oasigtm master mix lyophilised oasigtm master mix resuspension buffer blue lid c. Manual of standardized methods for veterinary microbiology.
883 1052 405 836 677 1429 538 134 1357 807 45 594 1387 293 944 538 853 1016 183 959 1579 1007 672 1363 776 1529 118 498 1497 1014 1107 128 219 1466 425 925 104 1489 561 1099 23 453